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Background and Objective: Due to high prevalence of pre-menstrual syndrome (PMS) and pre-menstrual dysphoric disorder (PMDD) and its effect on the educational, professional activities and familial behaviors, this study was conducted to determine the prevalence of clinical manifestations of pre-menstrual syndrome and pre-menstrual dysphoric disorder in medical students. Methods: This descriptive-analytic study was done on 162 female medical students of Golestan University of Medical Sciences in Gorgan, Iran during 2010. Demographic characteristics and PMS and PMDD clinical manifestations questionnaire based on DSM-IV-TR and ACOG criteria was filled for each subject. Results: Mean age and menarche age of subjects was 22.2±2.5 and 13.3±1.2 years, respectively. 145 students (89.5%) were single. 57.4% and 22.8% of participants fulfilled the criteria of PMS and PMDD, respectively. The most frequent affective and somatic symptom was lethargy and fatigability (57.4%) followed by sensation of bloating and weight gain (45.7%). The lowest frequent somatic and affective symptoms were dyspnea (8%) and insomnia (1.2%), respectively. There was significant correlation between the prevalence of PMDD and chronical and menarche age (P<0.05). Conclusion: Pre-menstrual syndrome is a prevalent disorder in medical students of Golestan University of medical sciences in Iran.

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Background and Objective: Puberty is a period of transition from childhood to adulthood which is accompanied by physiological changes. Menarche age is an important puberty indicator for assessing growth status. Growth and maturity of the genitals are essential for a girl's reproductive health. This study aimed to investigate the relationship between uterine sonographic characteristics and dimensions with menarche and puberty in girls.
Methods: This descriptive-analytical study was performed on 76 healthy girls (aged 9-16 years) who were referred to the endocrinology clinic of Taleghani Hospital in Gorgan (Iran) during 2017-2020. Height, weight and age were recorded and uterine and ovarian dimensions were measured by pelvic sonography.
Results: There was a significant positive correlation between menarche age (r=0.79, P=0.001) and ovarian length (r=0.81, P=0.007), ovarian volume and the length of the largest side of the uterus (r=0.77, P=0.001). Height had a significant positive association with menarche age (b=0.082, P=0.002) and ovarian length in the second place (b=0.097, P=0.004). But there was an inverse relationship between menarche age and girls' weight.
Conclusion: An increase in the menarche age increases the size of the uterus and its volume.