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Background and Objective: The diagnosis of oral lesions can be more difficult than skin lesions, it either may be missed, or have no difference in color with near mucosa. The correct diagnosis is important, because treatment and prognosis either of them is different. The purpose of this study was to survey the pathological oral lesions in Ahwaz the capital city of Khozestan rpovince in South-West of Iran. Materials and Methods: This retrospective descriptive cross sectional study was done on 588 pathologic specimen, types of oral lesions, on patients referred to department of pathology, Imam Khomeini hospital in Ahwaz, since 1994 to end of 2004. Results: The mucosal oral lesions were more common in women than men (305 cases, 54%), the most lesions were benign (461 cases), the numerous lesions were nonspecific, most of the patients were in range of 20-30 years. The most common malignant tumor was squamous cell carcinoma and the rarest malignant tumor was malignant melanoma that all of them were on lower lip. The most common site for lesions was lower lip (155 cases, %27.6). The malignant cases were more common in men than women. Conclusion: This study showed the benign mucosal oral lesions were more common in female, than males. The lower lip was the most common site which is similar to other reports. Squamous cell carcinoma was the commonest malignant tumor which has a correlation with other studies.

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Background and Objective: Lichen planus presents with chronic, inflammatory mucocutaneous lesions with almost 1-2% prevalency without any relation to demographic variables. This study was done to describe the clinical pathologic features of lichen planus patients in Mashhad, Iran. Materials and Methods: In this descriptive study, demographic data (age and sex) and some factors such as histology, form and anatomical zone of lesions were recruited from patient’s medical records and pathological slides revised. Data analyzed by using SPSS-13 software and chi-square and T student tests. Results: 309 patients (177 male, 132 female) were enrolled. Mean age was 40.12±16.3 years-old and patients were categorized mostly in 41-50 years age group. Clinical presentation in 44% was plaque and 41.7% with papules, 23.9% hyper pigmented, 26.9% scaled, 4.9% annular form and 2.9% linear. 45.6% of patients had classic histo-morphology and 25.9% of them had hypertrophic form. There was not any relationship between lesion histopathology with either sex or age. Anatomical zone had a significant relation with histopathology of lesion (P<0.05). Conclusion: This study showed that the prevalence of genital and mucousal lesions was lower than reported in other studies in various parts of the world.

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Background and Objective: The Detection of neurologic signs for topographical disorders in central nerves system can prevent unnecessary neuroimaging techniques such as MRI. This study was performed to determine the diagnostic value of physical examination for topographic detection of infratentorial lesions in patients with cerebrovascular syndromes. Methods: This descriptive study was done on 200 patients with cerebrovascular syndrome in Qaem Hospital in Mashhad, north-east Iran during 2011. Regarding to topographic physical examination, sensitivity, specificity, positive and negative predictive value and accuracy of signs of syndromes were compared to MRI as gold standard method. Results: The accuracy of tetraparesis and crossed syndromes for localization of brain lesion in brainstem was 79% and 83%, respectively. The accuracy of hemiataxia for localization of brain lesion in ipsilateral cerebellar hemisphere was 98%. The accuracy of Wallenberg syndrome for localization of brain lesion in posterolateral medulla was 98%. Conclusion: Using clinical neuro-examination skills and accurate topographic physical examination can prevent unwanted MRI technique for the diagnoses of cerebrovascular syndromes.