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Showing 1 results for Anti-Mullerian Hormone
Shamim Mosallami , Moghadaseh Jahanshahi , Fatemeh Sadat Hosseini , Somayeh Livani , Sima Besharat,
Volume 27, Issue 4 (12-2025)
Abstract
Background and Objective: Pregnancy success in infertile women depends on various factors, including oocyte quality, immunological factors, and endometrial receptivity. To evaluate ovarian reserve, parameters such as age, follicle-stimulating hormone (FSH), anti-Müllerian hormone (AMH), and antral follicle count (AFC) are considered. This study was conducted to determine the relationship of AFC and AMH with ovarian response in infertile women referring to an infertility center.
Methods: This descriptive-analytical study was conducted on 50 women (mean age = 33.88±5.32 years) who were candidates for assisted reproductive technology (ART) at the Nahal Infertility Center, Shahid Sayad Shirazi Hospital, in 2020. Serum levels of AMH, FSH, luteinizing hormone (LH), complete blood count (CBC), liver function tests (LFTs), thyroid function tests (TFTs), blood urea nitrogen (BUN), creatinine (Cr), and prolactin (PRL) were measured using enzyme-linked immunosorbent assay (ELISA), while FSH levels were measured via radioimmunoassay (RIA). Transvaginal ultrasound was performed on the third day of the menstrual cycle to determine the AFC.
Results: The mean duration of infertility was 4.8±2.8 years. Thirty-three women (66%) had primary infertility, and in 35 cases (70%), the cause of infertility was related to female factors. The mean and standard deviation serum levels of AMH and AFC were 4.8±4 ng/ml and 9±5 ng/ml, respectively. Poor ovarian response to treatment was observed in 8% of cases. Ovarian response showed a statistically significant correlation with AFC (P<0.05). Furthermore, AFC and AMH indices had significant statistical correlations with the ovarian response (P<0.05).
Conclusion: The AFC and AMH indices can be considered reliable predictors of ovarian response in infertile women.
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