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Background&Objective: Heavy metals have a high resistance against degradation. So their amounts in human food chain, such as fish, may be increased even several times either in water or air, due to bioaccumulation. These amounts are potentially dangerous to human. This study was done to determin of heavy metals in edible tissue of Lutjans Coccineus and Tigeratooh Croaker in the Persian Gulf. Materials&Methods: 60 samples of Lutjans Coccineus and Tigeratooh Croaker were collected randomly after preparation and chemical digestion for trace elements determination. Pb, Cr, Cd and Ni were determined by flame atomic absorption in 2003. Results: Average value of Pb, Cr, Cd and Ni in the edible tissues of two fish species, Lutjans Coccineus 0.442,0.333,0.063 and 0.322 and Tigeratooh Croaker of were 0.48, 0.062, 0.064 and 0.48 ppm (dry weight basis), respectively. Conclusion: Results indicated that the mean concentrations due to heavy metals in these two species were less than acceptable limit of WHO, but related concentrations of Pb, Ni, Cd and Cr in 27%, 25%, 8% and 3% of individual studied samples respectively were more than upper acceptable limit of WHO.

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Background & Objective: Gorgan Gulf, with unique environmental value, has been located at the eastern south region of the Caspian Sea. It has not only valuable fish species such as strugen, Caspian roach, carp and vobla fish which supply a great part of daily protein need of our country and the world, but also its beaches are used for swimming. Therefore Lack of observation for environmental regulations result in entrance of microbial pollutants into Gorgan Gulf and creates dangers both for human health and for marine environment. So the evaluation microbial pollution for these beaches and comparing them with standards is an essential need. This study was done to evaluate microbial pollution for Caspian Sea at Gorgan Gulf. Materials & Methods: 40 sea water samples were collected during spring and autumn of 2004 at Gorgan Gulf for evaluation of sea water in Gorgan Gulf microbial pollution and also the mean total number of bacteria, coliforms, fecal coli forms and fecal streptococci was determined by standard method. Results: The results indicated that the mean total number of bacteria, coli forms, fecal coli forms and fecal streptococcus were 5001/1cc, 1555/100cc, 817/100cc and 59/100cc respectively. Conclusion: Mean results compared with related standard (both for swimming beach and piscicultres) and we found that Gorgan Gulf beaches have been polluted for swimming applications, but it is not the case for piscicultures.

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Background and Objective: In clinical situation, pain occurs during intravenous Catheterization (IVC). Finding methods to reduce pain related with insertion of Angiocut. This study was performed to evaluate the effect of types of Transcutaneous Electrical Nerve Stimulation (TENS) on the pain severity regarding to insertion of Angiocut is very important. This study was performed to evaluate the effect of types of transcutaneous nerve stimulation (TENS) on the pain severity regarding to insertion of Angiocut. Materials and Methods: This clinical trial study was performed on the 80 patients of Internal and CCU wards of Fatemieh Hospital in Semnan, Iran during 2001. In this study, severity of pain related with insertion Angiocut assessed and compared in four conditions No TENS, low TENS (5 Hz), high TENS (100 Hz) and burst TENS (with frequence 100 Hz And burst frequence 2 Hz). The severity of pain measured by testes visual analogue scale (VAS), One-way ANOVA, Tukey, and Dunnett tests were used for comparing means of pain severity in different conditions. Results: Findings showed significant difference between severity of pain during Angiocut insertion in four conditions (P<0.05), so that the lower intensity of pain was in the high-TENS group, while higher pain was in the No TENS group. Significant difference was between intensity of pain in the No TENS group with high TENS and burst TENS group (P<0.05), but no significant difference was between low TENS and No TENS groups. Conclusion: This study showed that TENS was a effective method to reduce pain during Angiocut insertion. The lowest severity of pain was obtained in high TENS method. therefore, high TENS method can suggest as a effective method to reduce pain during Angiocut insertion.

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Background and Objective: The incidence of ectopic pregnancy is increasing due to artificial reproductive technology and increasing rate of sexual transmitted diseases. Ectopic pregnancy is the most common cause of maternal mortality in the first trimester and it reduces the chance of future successful pregnancy. Identifying the risk factors can help to reduce the maternal mortality and morbidity due to early diagnosis and on time treatment. This study was carried out to assess the risk factors in ectopic pregnancy in northern, Iran. Materials and Methods: This case control study was carreid out on 150 patients with ectopic pregnancy as cases and 300 women with normal pregnancy as controls. The subjects were selected from teaching hospital in Babol in northern Iran, during 2005-09. The risk factors include history of tuble surgery, ectopic pregnancy, cesarean section, pregnancy with IUD, infertility, assisted fertility with IUI, multiple partener, pre-eighteen years marriages were recorded for each subject by direct interview and file. Data were analyzed using SPSS-16 and Chi-Square and exat Fisher tests. Results: Theraputic assisted fertility with IUI (95% CI: 3.02-185.09, OR: 23.6, P<0.05), previous ectopic pregnancy (95% CI: 1.90-73.94, OR: 8.19, P<0.05) and cesarean section history (95% CI: 1.1-2.6, OR: 1.7, P<0.05) increased the possibility of ectopic pregnancy. There was not significant differnces between pre- eighteen years marriages, infertility history and multiple partener in cases compared to controls. Conclusion: This study showed that assisted fertility with IUI, previous tubal surgery, pregnancy with IUD, previous ectopic pregnancy and cesarean section are the main risk factors of ectopic pregnancy in northern, Iran.

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Background and Objective: Human immunodeficiency virus (HIV) pandemic is increasing word-wide. Tuberculosis is the main cause of death and low quality of life in HIV infected patients. The prevalence of Tuberculosis in HIV infected patients varies in different areas according to socioeconomic, cultural and geographical situation. This study was done to asses the pulmonary Tuberculosis risk factors in hospitalized HIV positive patients in Ahvaz, Iran. Materials and Methods: In this data based study all medical files of admitted HIV positive patients in Razi hospital in Ahvaz in south west of Iran were reviewed during 2001-09. Demographic characteristics and HIV Tuberculosis related variables were analyzed using SPSS-16, Fisher's exact test and Odds Ratio. Results: Out of 123 HIV cases 99 (80.5%) were injecting drug user (IDU), sixty eight (55.3%) had imprisoment history. Eighty one patients (65.8%) had Tuberculosis, in which 46 had co-morbidities such as infective endocarditis or viral hepatitis, 79 cases were IDU, 61 cases had imprisonment history and 24 cases had CD4 count below 200. There was a significant association between Tuberculosis and IDU, imprisonment and CD4 count (P<0.05). Conclusion: This study showed that the rate of Tuberculosis in HIV positive patients is higher than the rate in previous studies performed in Iran. Also exposure to Tuberculosis cases in prison, IDU and low CD4+ T- lymphocyte count are the main risk factors for Tuberculosis acquisition.

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Background and Objective: Adiponectin is an adipocyte-secreted hormone. Low levels of Adiponectin may indicate the insulin resistance and development of diabetes. The regular exercise therapy induces insulin resistance to be reduced. Glucose uptake increase in muscles, increased adiponectin levels and decreased of HbA1c in diabetic patients. This study was designed to evaluated the effect of down-hill and up-hill running exercises on the adiponectin and serum glucose in type-2 diabetic patients. Materials and Methods: This clinical trial study was conducted on 28 patients (13 male and 15 female), age 40 to 60 years, with type-2 diabetes, in neuromuscular rehabilitation research center, Semnan, Iran during 2009. Participants were assigned randomly in one of the two experimental groups, eccentric or concentric exercise using treadmill. Before and after control and intervention period, glucose, HbA1c and adiponectin serum were measured in both groups. Data were analyzed using SPSS-18, Kolmogorov-Smirnov, Repeated Measures ANOVA, Tukey and independent t tests. Results: Eccentric and concentric exercise significantly decreased glucose, HbA1c and also increased adiponectin levels (P<0.05) in type-2 diabetic patients. However, eccentric exercise also significantly reduced glucose and HbA1c and increased adiponectin levels compared to the concentric exercise (P<0.05). Conclusion: This study showed that eccentric exercise are more effective than concentric exercise to reduce and control the blood glucose level and improve serum adiponectin in type-2 diabetes mellitus patients.

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Background and Objective: Post-operative nausea vomiting (PONV) and laryngospasm are the most common of complication following surgery. This study was conducted to compare the incidence of laryngospasm and PONV after pediatric infra umbilical surgery using two anesthetic methods: control ventilation and spontaneous respiration. Materials and Methods: This double-blind clinical trial study was conducted on 192 children with 2-7 year-old undergoing infra-umbilical surgery of ASA-I class with the estimated operation period of an hour in Tehran pediatric hospital, Tehran-Iran during 2009-10. The patients were randomly divided into two groups: controlled ventilation and spontaneous respiration. After anesthetization, Atracurium was injected to the control ventilation (CV) group and anesthesia continued with mechanical ventilation. For the patients of the second group (spontaneous respiration/SR), after the gradual increase of the dose of halothane and certainty of the optimal depth of anesthesia, patients were intubated to allow spontaneous respiration. After intubation, all patients were anesthetized with Halothane 1-2% and the N2O/O2. The rate of nausea, vomiting, laryngospasm, excessive post-operative discharge was recorded. Data were analyzed using SPSS-13, student’s t-test, chi-square and Fisher’s exact tests. Results: Post-operative nausea was non significantly higher in CV group (8%) than SR (6.52%). The rate of vomiting was higher in CV (16%) as compared to SR group (2.17%). (P<0.001, RR=8.57, CI: 1.91-38.41). The rate of laryngospasm at the end of the surgery was higher in CV group (15.21%) as compared to SR group (26%) (P<0.02, RR= 0.94, CI: 0.05-1.77). The rate of excessive discharge at the end of the surgery was significantly higher in CV group (52%) in comparison with SR group (11.95%) (P<0.001, RR=0.94, CI: 0.05-1.77). Conclusion: This study showed that in infra-umbilical surgeries in a period of less than an hour the incidence of post-operative vomiting and laryngospasm is higher in control ventilation group than spontaneous respiration group, which might be due to the injection of neostigmine to counter-act the effects of muscle relaxants.

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Background and Objective: Some studies have shown that pregnant women with abnormal glucose challenge test (GCT) and normal oral glucose challenge test (OGTT) have the chance of adverse pregnancy outcomes including macrosomia, pre-eclampsia and increase of cesarean section rate. This study was performed to determine the pregnancy outcomes in women with abnormal glucose challenge test. Materials and Methods: This case –control study was done on 60 pregnant women with abnormal GCT (more than 130 mg/dl) and normal OGTT and 67 pregnant women with normal GCT (less than 130 mg/dl) in Kermanshah ,Iran during September 2010-March 2011. Results: Delivery with Vacum, polyhydroamnus, pre-eclampsia pyelonephritis and low birth weight significantly was higher in cases than controls (P<0.05). But there was a non significant difference in stillbirth, neonatal abnormality, neonatal respiratory distress and shoulder dystocia between case and control groups. Conclusion: Polyhydramnious, pre‌eclampsia and pyelonephrities and low birth weight are more frequent in pregnant women with abnormal GCT and normal OGTT in compare to pregnant women with normal GCT.

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Background and Objective: Enterotoxigenic Escherichia coli (ETEC) are the most common agent which causes diarrhea, worldwide. ETEC is colonized along the cells and then producing heat-labile (LT) and heat-stable enterotoxigenic which enter into intestinal epithelial cells and causes water and electrolyte loss from intestinal epithelial cells and eventually cause diarrhea.This study was done to detect the heat-labile toxin in Enterotoxigenic Escherichia coli using PCR-ELISA technique. Methods: In this descriptive study, DIG-labeled PCR products were bounded to streptoavidin-coated wells of a microtiter plate and detected by anti-DIG–peroxidase conjugate. The biotin-labeled internal probe was used for verification of PCR products. Results: Heat-labile toxin was detected by PCR-ELISA method. The sensitivity of heat-labile toxin was 1.9 ng. This method did not cross-react with bacteria from this variety. Conclusion: PCR-ELISA method is 100 times more sensitive than conventional PCR method and due to lack of agarose gel and electrophoresis device it can be a good alternative to traditional method.

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Background and Objective: Resistance of Staphylococcus aureus to antibiotics is one of the major global health problems in human societies. Thus, evaluation of pattern of antibiotic resistance in its different strains is very important. This study was carried out to evaluate the antibiotic resistance in Staphylococcus aureus isolated from clinical samples by disk diffusion and PCR methods.

Methods: In this laboratory- descriptive study, 50 isolates of Staphylococcus aureus to be identified from clinical specimens. Methicillin resistance was examined using PCR and antibiotic susceptibility of isolates was tested by disk diffusion method.

Results: 50 isolates were resistant to methicillin, ampicillin and penicillin. The resistance of isolates to erythromycin, Gentamicin, Clindamycin and Ciprofloxacin were 48%, 34%, 34%, 34%, respectively. The PCR method showed that 98% of Methicillin Resistance of Staphylococcus aureus isolates carried the methicillin resistant gene.

Conclusion: This study indicated that 98% isolates harbor mecA genes and more resistant to methicillin related mecA genes.

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Background and Objective: Yersinia is a gram-negative bacillus that cause diarrhea through consumption of contaminated food and water.  This study was performed to identify the atypical Yersinia virulence markers isolated from children with diarrhea.

Methods: This descriptive cross -sectional study was done on 384 fecal samples of 0- 14 years old children admitted at children medical center from August 2011 to August of 2012. Fecal samples, for the enrichment, after 21 days of incubation in alkaline buffer with pH=7.2 at 4degree C, on days 7, 14 and 21 samples were cultured on CIN agar and Mac agar and then confirm the differentiation atypical Yersinia from other typical Yersinia species from fermentation of different sugars. Isolates were tested for marker of virulence including calcium dependence, auto agglutination, Congo red uptake and binding of crystal violet.

Results: Out of 384 stool samples, 4 (1.04%) were infected with Yersinia (Yersinia frederikseni, Yersinia kristensenii and Yersinia enterocolitica). Out of these three, only two samples in association was positive with virulence markers.

Conclusion: Phenotypic markers can be used to study the properties of phenotypic strains of Yersinia.

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Background and Objective: Permanent first molars are susceptible to caries due to their particular anatomical form, early development and lack of knowledge of parents about their permanence. This study was conducted to determine the index of first permanent dental careis (DMF6) and some of its related factors in 12 year-old students.
Methods: This descriptive-analytical study was carried out on 400 students (200 females and 200 males) using combined method (stratified and cluster sampling) from public and non-governmental schools in Gorgan, northern Iran during 2015-16. First permanent molar examination was carried out. The parents' education level, frequency of toothbrushing and daily consumption of sugar-containing snack foods was recorded in a questionnaire. Each decayed, missing and filled first permanent molar tooth was given number one. These numbers were combined to compute the DMF6 index for each individual.
Results: The DMF6 index was zero in 19.5% and the DMF6 index was determined to be between
1 and 4 in 80.5% of the children. The mean DMF6 index was 2.23±0.07 and significantly higher in girls (2.39±0.10) than in boys (2.07±0.11) (P<0.05). The DMF6 index decreased with increasing parental education and the frequency of brushing and reducing consumption of sugary meals.
Conclusion: Dental caries prevalence among 12-years-old students in north of Iran is higher (2.23) than global standard until 2020 (lower than 1). Gender of child, parent’s education, frequency of toothbrushing and consumption of sugar-containing snack foods plays an important role in the rate of dental caries.

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Background and Objective: Mupirocin is a secreted antibiotic inhibitor of Isoleucine-tRNA, a bacterial synthetase that is used against yellow wounds from Streptococcus pyogenic and Staphylococcus aureus. This study was carried out to determine the plasmid resistance of mupirocin in Staphylococcus aureus strains isolated from clinical specimens of the skin of hospital employees and hospitalized patients.
Methods: This descriptive study was performed on 150 strains of Staphylococcus aureus isolated from clinical specimens of the skin of patients and employees of three hospitals in Qom, Iran during
2014-15. In order to confirm the identity of Staphylococcus aureus isolates, conventional biochemical methods were used. Also, PCR of srRNA16 was used for molecular confirmation of isolates. The presence of mupA (iles-2) and mupB plasmid genes was investigated using PCR method and AluI enzyme digestion plan was performed for them. Disc diffusion method was used to demonstrate resistance to mupirocin.
Results: Seven isolated samples (4.66%) were resistant to mupirocin. All Mupirocin-resistant isolates possessed PCR-positive mupacysin mupirocidal genes (iles-2) and mupB, and all plasmid genes were resistant to all resistant specimens. Genotyping of mupB gene was able to isolate samples from patients and staff as well as male and female.
Conclusion: The prevalence of mupirocin-resistant Staphylococcus aureus isolated from skin specimens was low.

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Background and Objective: The trigger point is the irritable point associated with a tight band of skeletal muscle which is painful against stress and strain. The real goal in treating trigger points is to achieve a degree of pain relief so that the sufferer can return to his usual activities and functions in spite of some pain. This study was carried out to compare of two methods of sports massage and cold stretch on the threshold of pain in passive trigger points in shoulder girdle muscles of the female volleyball players.
Methods: In this quasi-experimental study, 32 females national volleyball palyer who has a latent trigger point in the shoulder girdle region were non-randomly divided into to three groups of sports massage (n=11), stretching along the cold (n=11) and control (n=10) groups. Threshold of pain test was carried out in two steps, prior and immediately after sports massage and stretching along the cold.
Results: The mean of pain threshold prior and immediately after the study in control group was 38.84±11.348 and 35.16±9.311, respectively. The mean of pain threshold prior and immediately after the study in sports massage group was 39.40±9.88 and 43.54±9.63, respectively. This differernce was not significant. The mean of pain threshold prior and immediately after the study in stretching along the cold group was 39.22±10.57 and 41.10±10.95, respectively. This differernce was not significant.
Conclusion: Sports massage and stretching along the cold did not significant effect on the threshold of pain in passive trigger points in shoulder girdle muscles of the female volleyball players.

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Background and Objective: Lung volume loss, airway obstruction and air flow limitation, and also hypertension are risk factors for mortality in patients with type 2 diabetes. This study was done to determine the effect of supplementation of saffron and exercise training on blood pressure changes, pulmonary function and spirometric indices in obese and overweight women affected by type 2 diabetes.

Methods: In this quasi-experimental study, forty-eight type 2 diabetic obese and overweight women were non randomly divided into four equal groups including placebo, saffron + training, training + placebo, saffron plus placebo). The saffron group + training and training + placebo groups did aerobic training with intensity of 60-75% of maximal heart rate for 8 weeks (three sessions per week). A daily dose of 400 mg of saffron sprout powder (once a day) was used for two months. The variables were measured in the pre-test, 48 hours and two weeks after the last training session.

Results: Intra-group results showed a significant increase in pulmonary function variables (VO2max, FVC, FEV1, FVC/FEV1, PEF, MVV), and significant reduction in systolic blood pressure and anthropometric indices (weight, BMI, and body fat percentage) in all three groups of exercise, saffron and practice + saffron (P<0.05). However, the results intra-group showed a significant difference in the above variables between the exercise + saffron supplement group in compared to other intervention groups (P<0.05), also, the highest effect was observed in the exercise + supplemental group.

Conclusion: According to the results of this study, saffron with exercise led to significant improvement in pulmonary volume and capacities, as well as a decrease in blood pressure in obese and overweight women affected by type 2 diabetes.

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Background and Objective: Due to the properties of herbal remedies and their lesser side effects than chemical drugs, much attention has now beeing paid to herbal treatments. The aim of this study was done to evaluate the antinociceptive and anti-inflammatory effects of hydroalcoholic extract of aerial parts of Ruscus aculeatus.
Methods: This experimental study was performed on 80 male NMRI mice (6-8 weeks) weighing 23-25 gr. Animals were randomly allocated into 5 groups including: control group (distilled water), positive control group (morphine 10 mg/kg/bw in pain test and dexamethasone 15 mg/kg/bw in inflammatory test) and three groups receiving 75, 150 and 300 mg/kg/bw Hydroalcoholic extract of Ruscus aculeatus L. The pain was evaluated by formalin test and an investigation of inflammation conducted by xylene induced ear-edema.
Results: The hydroalcoholic extract of Ruscus aculeatus L significantly reduced acute pain at 300 mg/kg/bw in compared to control group (P<0.05). Inhibition percent was 60% for acute pain and 85% in morphine group. Also, this plant caused significant reduction of formalin induced chronic pain at 150 and 300 mg/kg/bw doses in compared to the control group (P<0.05). At 150 and 300 mg/kg doses of Ruscus aculeatus L, inhibition of chronic pain was 71%, and 94%, respectively in compared with 97% inhibition in morphine group.
Conclusion: Hydroalcoholic extract of Ruscus aculeatus L at the dose of 300 mg/kg/bw reduces acute and chronic pain and at the dose of 150 mg/kg/bw reduces acute pain in laboratory animals.

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Background and Objective: Mood disorders such as depression, anxiety, stresses, and low sleep quality are common among overweight / obese people. Accumulating evidence support the role of diet quality in brain function and behavior. This study was done to determine the relationship between dietary energy density and indices of mental health in overweight and obese women.
Methods: This descriptive-analytical study was performed on 301 women, referring to Tehran health centers, with mean BMI 30.7±3.7 kg/m² aged 18-56 years during 2017-18. Based on a semi-quantitative food frequency questionnaire, dietary energy density was calculated by dividing the total dietary energy intake from consumed food (kcal/d) by the total weight (g/d) of consumed foods (excluding beverages). Physical activity was measured using International Physical Activity Questionnaire (IPAQ). The questionnaire includes 7 items to assess the intensity of activities by the vigorous, medium, and light for at least 10 minutes during the last week. Mental health was assessed using the 21-question version of the Depression Anxiety Stress Scales (DASS-21) and the Pittsburgh Sleep Quality Index was applied for screening sleep quality. Weight, height, BMI, hip, and waist circumference were measured for all participants.
Results: Women in the highest quartile of dietary energy density had higher systolic and diastolic blood pressure but lower serum triglyceride (P<0.05), compared with subjects in the first quartile. Univariate (95% CI: 1.01-4.56, P=0.04, OR=2.15) and multivariate (95% CI: 1.13-5.79, P=0.02, OR=2.56) logistic regression analysis, adjusted for age, BMI, and physical activity, showed that dietary energy density was significantly related to increased risk of stress. No significant association was detected between dietary energy density with sleep quality, depression, and anxiety.
Conclusion: Dietary energy density was directly associated with the presence of stress, but not depression, anxiety and low sleep quality.

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Background and Objective: Inactivity and physical inactivity can be one of the main causes of obesity, especially abdominal obesity, hypertension, cardiovascular disease. Abdominal obesity is a serious risk factor for cardiovascular disease which being inversely related to VO₂ max (maximal oxygen consumption). This study was done to determine the non-invasive monitoring of cardiorespiratory fitness and its association with abdominal obesity in men.
Methods: In this descriptive-analytical study, men aged 20-60 years were selected by cluster sampling from different areas of the centers of the three provinces including Qazvin, East Azarbajan and Hamedan in Iran. In accordance with Morgan method, the sample size was 384 men from all provinces which were divided into four age groups. Aerobic power of subjects was assessed by utilizing Bruce, Rockport, Pedometer and International Physical Activity Questionnaire (IPAQ). Waist-to-height ratio (WHtR), Waist-to-hip ratio (WHR), Body adiposity index (BAI), Surface-Based Body Shape Index (SBSI) and body mass index (BMI) was measured for each subject.
Results: Based on the results, in all three provinces as well as the provinces themselves, VO₂ max was significantly different between different age groups (P<0.05). Also, in abdominal obesity indices, a significant difference was in abdominal obesity indices BMI, WHR, WHtR and BAI (P<0.05). There was a significant inverse correlation of the VO₂ max with central obesity indices, except for the SBSI.
Conclusion: Reducing physical activity and consequent cardiorespiratory fitness led to an increase in abdominal obesity indices in different age groups that shows a significant inverse correlation of the VO₂ max with central obesity indices, except for the SBSI.

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Background and Objective: Obesity plays an important role in the development of chronic diseases including diabetes, hyperlipidemia, and cardiovascular diseases (CVD). This study was conducted to evaluate the association of the age of onset of obesity with resting metabolic rate (RMR) in overweight and obese women during adulthood.
Methods: This descriptive-analytical study was done on 295 overweight and obese women aged 18-50 years in Tehran, Iran. The anthropometric measurements of all participants were measured. Dietary intake and total daily energy intake were assessed by using a semi-quantitative food-frequency questionnaire (FFQ) which the list including 147 food items. Resting metabolic rate was measured by indirect calorimetric method. In order to measure the physical activity International Physical Activity Questionnaire (IPAQ) was used. The questionnaire includes 7 items to assess the intensity of activities by the vigorous, medium, and light for at least 10 minutes during the last week.
Results: There was a significant difference between those whose age of onset of obesity was under 18 or over 18, in RMR per body weight (kg) (Beta: 0.16, CI: 0.11 to 0.00, P: 0.03). In addition, it was seen a significant inverse correlation between age of onset of obesity and body weight (Beta: -0.11, CI: -0.30 to 0.00, P: 0.005) and adipose tissue content (Beta: -0.13,
CI: -0.23 to -0.01, P: 0.02). After adjustment for confounders including (age, physical activities, and energy intake), the correlations still remain significant.
Conclusion: Age of onset of obesity was associated with increased weight and fat and decreased resting metabolic rate in adulthood. In fact, people with lower obesity age have higher body weight and fat and lower RMR.

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Background and Objective: Overexposure to electromagnetic waves produces by computer cause health disorders by users. This study was performed to determine the employer's exposure risk to electromagnetic fields from monitors of computers in north of Iran
Methods: This descriptive-analytical study was performed on 100 of computers using by 100 employee users (69 males and 31 femals) with the mean age of 40.83±7.37 in Gomishan county, Golestan province in north of Iran during 2018. The intensity of the magnetic and electric field caused by computers was measured at 30, 50 and 60 cm intervals and in four directions from the front, back, right and left side of the monitor using SVENSK standard method. The intensity of fields was measured by TM-190 instrument. Data were compared with OEL (Occupational Exposure Limit), MPRII and TCO (The Swedish Confederation of Professional Employees). The NIOSH (National Institute for Occupational Safety and Health) standard questionnaire was used to assess the side effects of working with computers. The health problems in employee users were recorded.
Results: The mean±SD of the intensity of the electrical waves was 103.63±33.62 v/m that was less than the standard values. The mean±SD of the intensity of the magnetic waves was 0.1±0.09 mA/m that was higher than the TCO, MPRII standard values and less than OEL. The maximum magnetic-field invasion from the standard range with an average of 157.04 mA/m is on the front of the monitors, at a distance of 30 cm and the lowest of them with a mean of 19.2 mA/m for the off-mode computer and at a distance of 60 cm from the mantle. There was a significant difference between the time of working with computer in the day with burning eye, headache and eye fatigue. There were no significant difference of clinical symptoms in men and women and fatigue syndrome.
Conclusion: The electrical waves of monitor of computers were lower than standard limit in all studied conditions, but the magnetic waves were much higher than standard limit.