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Showing 82 results for Type of Study: Short Communication

Somayeh Jahanabadi , Abolhasan Halvani , Sareh Rafatmagham , Mohammadjavad Berizi ,
Volume 27, Issue 1 (3-2025)
Abstract

Background and Objective: The coronavirus disease 2019 (COVID-19) has shown an increasingly rapid progression in individuals with underlying diseases or comorbidities, frequently culminating in mortality. This study was conducted to compare certain risk factors associated with mortality due to COVID-19 in patients at Shohadaye Kargar Hospital in Yazd.
Methods: This descriptive study was conducted on 120 surviving (recovered) polymerase chain reaction (PCR)-positive COVID-19 patients (55 males and 65 females) with a mean age of 52.8 ± 18.88 years and 60 deceased PCR-positive COVID-19 patients (34 males and 26 females) with a mean age of 75.4 ± 15.4 years at Shohadaye Kargar Hospital in Yazd, Iran during 2019-2020. Census sampling was performed on all confirmed positive cases of COVID-19. Variables including age, gender, cigarette use, presence of diabetes, hypertension, pulmonary and cardiovascular diseases, and malignancies, which were collected in Yazd Province by the Provincial Coronavirus Committee, were evaluated.
Results: The variables of gender, cancer, cigarette use, asthma, and deep venous thrombosis (DVT) did not show any statistically significant differences between the recovered and deceased groups. The variables of diabetes, hypertension, ischemic heart disease, chronic obstructive pulmonary disease (COPD), and age showed statistically significant differences between the two groups (P<0.05).
Conclusion: Advanced age and the presence of hypertension and diabetes are considered risk factors in COVID-19 patients.



Bahman Aghcheli , Seyed Amirreza Hejazian , Ghazaleh Alizad , Sadeghali Azimi , Alireza Tahamtan ,
Volume 27, Issue 4 (12-2025)
Abstract

Background and Objective: The coronavirus disease 2019 (COVID-19) pandemic has revealed significant variability in clinical outcomes driven by demographic, geographic, and underlying factors, highlighting the need for a better understanding of disease progression. This study was conducted to determine the clinical characteristics, outcomes, and predictors of disease severity among hospitalized COVID-19 patients in Gorgan, Iran.
Methods: This descriptive-analytical, cross-sectional study was conducted on the data of 736 hospitalized COVID-19 patients (58.6% male; mean age = 55 years; age range = 1–94 years) at the Fifth Azar Educational-Therapeutic Center in Gorgan during 2021. A convenience sampling method was employed, and patients were selected based on the completeness of their electronic medical records. Patients were categorized based on disease outcome (recovery/death) and disease severity (intensive care unit [ICU] admission/general ward admission). Demographic data, symptoms, and comorbidities were extracted from electronic health records. Inclusion criteria consisted of a confirmed diagnosis via reverse transcription quantitative polymerase chain reaction (RT-qPCR), while exclusion criterion included incomplete data or transfer to other medical centers.
Results: The mortality rate was 31.3%, occurring predominantly in the older adult age group (P<0.05). Due to disease severity, 21.2% of cases required ICU admission. Dyspnea was significantly associated with both mortality and disease severity (P<0.05). The prevalence of dyspnea was 62.6% among deceased patients compared to 37.4% in recovered patients. Comorbidities, such as cardiovascular diseases and chronic obstructive pulmonary disease (COPD), were significantly associated with increased mortality (P<0.05).
Conclusion: Old age and specific comorbidities were identified as key predictors of severe outcomes. Early identification of symptoms, particularly dyspnea, and targeted interventions are essential for high-risk groups.

 

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مجله دانشگاه علوم پزشکی گرگان Journal of Gorgan University of Medical Sciences
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This work is licensed under a Creative Commons — Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)