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Showing 52 results for Sin

Mohammad Mehdi Soltan Dallal , Mohammad Kazem Sharifi Yazdi , Alireza Monadi Sefidan , Gholamreza Hassanpour , Sara Sharifi Yazdi, Shabnam Haghighat Khajavi , Saeed Vahedi , Seyedeh Masoomeh Abrichamchian Langaroudi , Mahdieh Pourmoradian , Hedroosha Molla Agha Mirzaei ,
Volume 24, Issue 1 (3-2022)
Abstract

Background and Objective: Yersinia is water and foodborne organism that cause human gastroenteritis. This study was done to evaluate the frequency of Yersinia species isolated from children diarrheal samples and chicken meat in Tehran, Iran.
Methods: In this descriptive study 250 sample of diarrhea of children referred to the Children's Medical Center, Tehran, Iran and 250 samples of chicken were collected and examined for Yersinia infection during July 2016 to March 2017. Isolation method was performed based on initial enrichment in phosphate buffer for 3 weeks in refrigerator (cooling in c4 +) and then using KOH as secondary enrichment and culture on CIN agar medium. Biotyping method was used to determine pathogenic strains.
Results: In this study, 5(2%) isolates from pediatric diarrhea samples and 20 isolates (8%) from chicken meat samples were obtained from Yersiniaenterocolitica. Biotyping of human Yersiniaenterocolitica isolates identified 3 cases of biotype 1A, one case of biotype 1B, one case of biotype 2 and from chicken meat isolates, 16 isolates belonged to biotype 1A and 4 isolates belonged to biotype 1B.
Conclusion: Presence of common pathogenic 1B and non-pathogenic 1A biotypes in pediatric diarrhea samples and chicken meat can indicate the cause of diarrhea in children.
 
Masoumeh Ahmadpour Torki , Mojtaba Ranjbar , Mostafa Govahi, Majid Tafrihi ,
Volume 24, Issue 3 (10-2022)
Abstract

Background and Objective: Trametes versicolor is important for its medicinal rather than nutritional value. Given the various pharmacological activities of this plant, this study aimed to investigate the antioxidant and antimicrobial potential of the aqueous extract of T. versicolor.
Methods: In this descriptive-analytical study, an aqueous extract of T. versicolor was prepared. Antioxidant activity, flavonoid content and total phenol were measured by diphenyl picryl hydrazyl (DPPH) and reducing power (RP) methods, aluminum chloride (AlCl3), and Folin-Ciocalteu assays. The antibacterial and antifungal activity of the aqueous extract of T. versicolor on Staphylococcus aureus, Escherichia coli and Fusarium thapsinum was determined by the disk diffusion method. Butylated hydroxytoluene (BHT), ciprofloxacin and amphotericin-B were used as positive controls for antioxidant activity and bacterial and fungal strains, respectively.
Results: Total phenolic content was 27.6±0.38 (mg GAE/g), and total flavonoid content was 4.2±0.04 (mg QE/g). Based on DPPH radical scavenging activity, the extract of T. versicolor showed strong scavenging activity (93.8±1.2 %) with IC50 of 103.9±0.8 μg/mL when compared with the standard BHT (IC50 of 30.0±0.6 μg/mL). In addition, it was observed that increasing the concentration of aqueous extract of turkey tail increased the reducing power of iron. The zone of inhibition around the extract ranged from 13.0±0.65 mm (in F. thapsinum at 75 mg/ml) to 21±0.73 mm (in S. aureus at 300 mg/ml) (P<0.05).
Conclusion: The aqueous extract of  T. versicolor contains a significant amount of phenolic compounds and also has strong antimicrobial and antioxidant properties.
 
Seyed Rasool Hosseini Kohestani ,
Volume 25, Issue 0 (9-2023)
Abstract

Various sciences such as medicine, psychology, sociology, history, ethics, etc., each of them look at humans from a specific angle and study them. Therefore, in any science, including medicine, what constitutes the subject of that science and forms the basis of the problems of that science depends on the definition of that science of the nature and essence of man. Therefore; it is very important to look at human nature in the recognition of disease and its prevention and treatment. The present research, with descriptive analytical method and referring to library sources, aims to investigate the impact of non-material factors such as disobeying divine orders and moral vices in depriving mental health from the point of view of Islam. The findings of this research show; there are two general views about human nature: material and divine. Now; in medical sciences, in all three areas of disease recognition, prevention and treatment, depending on the acceptance of one of the two mentioned points of view, the data and, accordingly, the results will vary. It is obvious that, rejecting metaphysical dualism, the materialist view in medical studies defines its scope of research only on the axis of material and experimental factors and in opposite; the divine perspective considers the scope of the mentioned studies beyond material factors and includes non-material and spiritual factors as well. As a result: by assuming the divine perspective, it is shown that the causes of disease go beyond material factors and include non-material factors as well, and sin and disobedience to divine orders and moral vices have a direct effect on causing some diseases And on the contrary, observing religious and moral principles has an effect on maintaining and sustaining the health of the body as a cage of the soul.


Farida Abesi , Mehdi Hozuri , Fateme Aghaee,
Volume 25, Issue 1 (3-2023)
Abstract

Understanding maxillary sinus hypoplasia (MSH) and associated sinonasal variants is crucial for the success of diagnostic and therapeutic procedures in maxillary sinus and maxillary dental implant surgery. The aim of this study was to investigate a rare case of unilateral maxillary sinus hypoplasia associated with lower orbital floor displacement, without involving the Uncinate process. A 31-year-old woman presented to the Department of Oral and Maxillofacial Surgery at Babol Dental School for rhinoplasty without any complaints of headache or nasal congestion. She had no history of trauma, congenital or bone diseases/abnormalities. Cone Beam Computed Tomography (CBCT) images revealed left maxillary sinus hypoplasia, lower orbital floor, and increased thickening of the sinus mucosa. The patient's photograph also showed lower displacement of the orbital floor. The diagnosis of unilateral maxillary sinus hypoplasia in this study was based on clinical manifestations and coronal views of CBCT and CT scans. Symptoms of hypoplastic sinus include chronic headache, facial pain, voice problems, or may sometimes be asymptomatic. If the surgeon is not aware of the hypoplasticity of the sinus, complications during surgery may increase, including post-surgery complications such as visibility of the low orbital floor and resulting patient confusion. This study highlights the importance of using CBCT as a valuable diagnostic tool to identify anatomical variations and details of the hypoplastic sinus. This approach helps the surgeon to inform the patient and provide an appropriate treatment plan, especially in cases involving dental implants or sinus surgery.
 

Hamidreza Naserpour , Mehdi Khaleghi Tazji , Amir Letafatkar , Hooman Angoorani ,
Volume 25, Issue 1 (3-2023)
Abstract

Background and Objective: Long-standing groin pain (LSGP) is a common injury in ball games. This study aimed to compare the electrical activity of selected lumbopelvic-hip muscles during a single leg jump-cut maneuver in football players with LSGP and healthy players.
Methods: In this case-control study, 32 football players were divided into two groups: LSGP (n=16) and healthy (n=16). A force plate was used to determine the heel-contact and heel-off moment. The ground reaction forces and the average of three trials of the electrical activity of selected lumbopelvic-hip muscles during a single leg jump-cut maneuver were recorded bilaterally.
Results: At the heel-contact moment, the rectus abdominis and adductor longus muscles on the dominant side and the multifidus muscle on the opposite side showed significantly higher activity in the LSGP group compared to the healthy group (P<0.05). Similarly, at the peak of the vertical reaction force, the rectus abdominis and adductor longus muscles on the dominant side and the multifidus and gluteus medius muscles on the opposite side were significantly more active in the LSGP group (P<0.05). At the toe-off moment, the internal oblique, adductor longus, and gluteus medius muscles on the dominant side and the internal oblique, multifidus, and gluteus medius muscles on the opposite side were also more active in the LSGP group compared to the control group (P<0.05).
Conclusion: Long-standing groin pain causes changes in the electrical activity of muscle groups during different phases of the single-leg jump-cut maneuver, leading to increased dynamic stability and possibly an increased risk of overuse injuries, chronic injuries, economic consequences, and exclusion from sports activities.
 

Bahare Nikoozar , Negin Kazemi , Abbas Kiani-Esfahani , Mohammad Hossein Nasr-Esfahani , Marziyeh Tavalaee ,
Volume 25, Issue 3 (10-2023)
Abstract

One of the main spermatogenesis events is the replacement of histones with small proteins called protamines, which leads to chromatin's condensation in the sperm nucleus and protects it against possible damage. Today, tests such as aniline blue (AB), toluidine blue (TB), and chromomycin A3 (CMA3) staining are used based on different characteristics to evaluate sperm chromatin compaction. For the assessment of DNA fragmentation in sperm, several tests such as 8-hydroxy-2-deoxyguanosine (8-OHdG), TUNEL, Comet, sperm chromatin structure assay (SCSA), sperm chromatic dispersion (SCD), and acridine orange have been introduced that directly and indirectly assay DNA damage. The articles in PubMed and Google Scholar, as well as related books, from 2007 to 2022, were collected and reviewed based on keywords 8-OHdG, TUNEL, Comet, SCD, and acridine orange. So far, many studies have been conducted at the treatment level and on sperm chromatin tests, but the number of cases published so far is limited. Various sperm samples have been used in different studies, with different threshold limits in the tests. The sixth edition of the World Health Organization (WHO) book notes that each laboratory has its threshold limit. Therefore, in this review study, common methods of evaluating chromatin packaging and DNA damage are introduced, and the advantages and disadvantages of each test are discussed based on the latest achievements related to infertility.


Zahra Safavibayat , Nadereh Naderiravesh , Malihe Nasiri , Majid Daneshfar ,
Volume 25, Issue 3 (10-2023)
Abstract

Background and Objective: Loneliness is one of the problems experienced by the aging population, and the lack of social communication plays a major role in the emergence of loneliness. This study was conducted to determine the effects of telenursing on the loneliness of the elderly.
Methods: This field trial was conducted on 100 elderly people over 60 years of age who were selected by convenience sampling from the clients of Gonabad (Iran) community health centers during 2017. The elderly participants were randomly assigned to 2 groups of 50 people, intervention and control. Then, the demographic information questionnaire, the Informant Questionnaire for Cognitive Decline in the Elderly, and Dehshiri et al.'s Loneliness Scale were completed. The intervention group received face-to-face training by the researcher for 2 hours. There was no intervention for the control group, and the elderly received routine care from the family health unit. After the face-to-face meeting, phone calls were made by the researcher to the intervention group for 12 weeks. One month after the end of the intervention, the questionnaires were completed again by the two groups and evaluated and compared.
Results: The mean (standard deviation) score of loneliness was 60.82±21.07 and 57.48±18.76 before the intervention in the intervention and control groups, respectively, and this value after the intervention was 35.06±14.20 and 61.40±18.72, respectively, in the intervention and control groups. After the intervention, a statistically significant difference was found in terms of a reduction in the loneliness score of the elderly in the intervention group compared to the control group (P<0.05).
Conclusion: This study showed that telenursing was effective in reducing the loneliness of the elderly.


Golnoosh Tolue , Seyed Abdolhamid Angaji , Behnaz Beikzadeh , Hengameh Alibeik , Raheleh Roudi, Behzad Narouie ,
Volume 25, Issue 3 (10-2023)
Abstract

Background and Objective: Prostate cancer is a malignancy affecting men. Identifying risk factors for prostate cancer is crucial for the potential development of interventions and expanding our biological understanding of this disease. The present study investigated the association of rs1800896 and rs1800896 with prostate adenocarcinoma.
Methods: This case-control study was conducted on 176 men, including 78 patients with prostate adenocarcinoma (case group) and 98 men with benign prostatic hyperplasia (control group), who visited the Labafinejad Educational and Treatment Center in Tehran, Iran. Genotyping was performed using the Tetra ARMS-PCR (amplification refractory mutation system-polymerase chain reaction) method.
Results: There was no statistically significant difference between the case and control groups in the genotype frequency of rs1800896 and rs1465618. However, the rs1800896 polymorphism was associated with PSA levels less than or equal to 4 ng/mL (P<0.05). Significant associations were found between rs1800896 and rs1465618 polymorphisms and clinical features, such as perineural invasion (P<0.05).
Conclusion: The rs1800896 and rs1465618 polymorphisms were not associated with the risk of prostate adenocarcinoma.


Babak Ranjbar , Farida Abesi , Soraya Khafri ,
Volume 25, Issue 4 (12-2023)
Abstract

Background and Objective: Sinus extension is a physiological process that occurs in the growth cells of the paranasal sinuses and leads to increasing their volume over time, causing challenges in the dental implant process. This study was conducted to evaluate maxillary sinus morphometrics by cone-beam computed tomography (CBCT).
Methods: This descriptive-analytical study was conducted on the CBCT images of 100 people (52 male and 48 female) with a mean age of 45.32 ± 17.41 and the age range of 27 to 63 years referring to an oral and maxillofacial specialized radiology clinic in Babol, Iran during 2019. The amount of maxillary sinus extension in the panoramic-like view was recorded based on the amount of its extension in terms of the first anterior tooth and the last posterior tooth. In the new net technologies (NNT) software, in the section related to creating panoramic-like views, first, in the axial sections, the starting point of the maxillary sinus was specified from the occlusal side, and the mediolateral dimensions were measured at distances of 3 mm above and 3 mm below.
Results: The highest amount of maxillary sinus progress in the right anterior side was related to the mesial of tooth 5 (15%), and the highest amount of sinus progress in the left anterior side was related to the distal of tooth 3 (15%) and the mesial of tooth 4 (15%), which had no statistically significant differences. The most progress in the anterior area was related to the distal of the canine tooth and the mesial of the first premolar. The mean mediolateral sinus progress at 3 mm above the right nasal floor was higher in females than in males (P<0.05). Gender and age had no statistically significant relationship with maxillary sinus progress.
Conclusion: The maxillary sinus progress was almost equal in the left and right sides and also in males and females.


Mansur Mottahedy , Tahereh Bagherpour , Ardeshir Zafari, Nematolah Nemati ,
Volume 26, Issue 2 (7-2024)
Abstract

Background and Objective: Neural, hormonal, and mechanical factors regulate the expression of fast-twitch isoforms in developing and mature muscle fibers. The transcriptional mechanisms responsible for regulating the gene expression of myosin heavy chain types are not well understood. This study aimed to determine the effect of a single session of intense resistance exercise with glutamine supplementation on the relative expression of the alpha and IIX isoforms of the myosin heavy chain gene in male rats.
Methods: This experimental study was conducted on 30 adult male Wistar rats divided into three groups: control, intense resistance exercise (first experimental group), and fierce resistance exercise combined with glutamine supplementation (second experimental group). The exercise groups participated in a single session of resistance climbing on an inclined plane with 4 sets of 5 repetitions, 30 seconds of rest between repetitions, and 2 minutes of rest between sets. Glutamine supplement powder was dissolved in 100 ml of distilled water at a dose of 0.5 grams per kilogram of body weight and administered daily via gavage for 5 days. The expression of alpha and IIX isoforms of the myosin heavy chain gene was examined in the extensor digitorum longus muscle tissue.
Results: The relative expression of the alpha myosin heavy chain gene in the fast-twitch muscle fibers increased significantly in the first experimental group (1.93±0.298) and the second experimental group (1.65±0.195) compared to the control group (P<0.05). The relative expression of the IIX motor unit gene in the fast-twitch muscle fibers also increased significantly in the first experimental group (1.42±0.239) and the second experimental group (1.26±0.190) compared to the control group (P<0.05). The increase in the relative expression of the alpha myosin heavy chain gene in the first experimental group compared to the second experimental group was statistically significant (P<0.05). However, the increase in the relative expression of the IIX motor unit gene in the first experimental group compared to the second experimental group was not statistically significant.
Conclusion: Our study concludes that a single session of intense resistance exercise, with or without glutamine supplementation, significantly increases the relative expression of the alpha myosin heavy chain gene and the IIX motor unit gene in the fast-twitch muscle fibers of the extensor digitorum longus muscle in adult male rats. These findings provide valuable insights into the molecular


Atena Sadat Jamali , Farida Abesi ,
Volume 26, Issue 3 (10-2024)
Abstract

Background and Objective: The infraorbital canal (IOC) is located in the floor of the orbit and terminates at the infraorbital foramen below the orbital rim. The IOC is a crucial anatomical landmark for successful anesthesia in dentistry and oral and maxillofacial surgery. This study aimed to evaluate the position and dimensions of the IOC based on cone-beam computed tomography (CBCT).
Methods: This descriptive-analytical study was conducted on CBCT images of 250 individuals (105 males and 145 females) (mean age = 36.14±17.7 years) referring to a specialized oral and maxillofacial radiology clinic in Babol, Iran, during 2021-22. Three different types of IOC pathways from the sinus roof were measured: Completely located within the maxillary sinus roof (Type 1), located below the maxillary sinus roof (Type 2), and suspended from the maxillary sinus roof within the septum or lamella of the infraorbital ethmoid cell (Type 3). Additionally, the angles between the IOC and the infraorbital groove with the maxillary sinus roof, the angles between the IOC and the infraorbital groove, the lengths of the IOC and the infraorbital groove, and the distances of the IOC from various anatomical landmarks were measured. Distances of the IOC (mm) were evaluated from other anatomical landmarks according to gender and age groups.
Results: Overall, various pathways of the IOC from the sinus roof were 39.4% in Type 1, 53% in Type 2, and 7.6% in Type 3; the mean distance of the IOC to the infraorbital rim was 8.58±1.30 mm, and to the midpoint of the canine root was 10.16±0.81 mm. The mean length of the canal was 25.89±2.47 mm, and the infraorbital groove was 5.06±0.58 mm; and the mean angle between the IOC and the infraorbital groove was 153.20±3.28 degrees. In general, the distance of the IOC to the midpoint of the canine root on both the left and right sides was greater in males than in females, which was statistically significant on the left side (P<0.05). It was found that the length of the IOC and the angle between the IOC and the infraorbital groove on the left side had statistically significant correlations with age groups (P<0.05). The mean distance from the foramen to the infraorbital rim and the length of the IOC were proportional to the degree of nerve protrusion into the maxillary sinus; however, no significant correlation was found between the types of canals (degree of nerve protrusion) and gender.
Conclusion: Type 2 was the most common pathway of the IOC from the sinus roof. Although Type 3 was less common, due to the high risk associated with this type of canal, surgeons should be fully aware of the morphology and anatomical position of the IOC during sinus and orbital surgeries to reduce probable injuries.


Mohammad Pourmehdi , Mohammad Hadi Gharib , Ehsan Fattahi , Rouzbeh Shams Amiri ,
Volume 27, Issue 4 (12-2025)
Abstract

Background and Objective: The sphenoid sinus is one of the four paranasal sinuses located within the sphenoid bone and plays a crucial role in pituitary gland surgeries. This sinus is in close proximity to vital structures, including the internal carotid artery and the optic nerve. This study was conducted to radiologically evaluate sphenoid sinus anatomical characteristics using computed tomography (CT) scans of patients referring to selected imaging centers in Gorgan, Iran.
Methods: This descriptive-analytical study was conducted on 180 patients (100 females and 80 males; mean age = 35.69±13.07 years) referring for paranasal sinus CT scans or head and neck CT scans, prescribed by a specialist physician, to the Fifth Azar Educational-Therapeutic Center and Izadi Imaging Center in Gorgan, Iran, during July and August 2020. The sphenoid sinus volume and anatomical characteristics, including the type of pneumatization, presence of septa, and carotid canal protrusion and adhesion, were examined via CT imaging.
Results: Regarding the frequency distribution of sinus types based on the site of pneumatization, 151 cases (83.8%) were postsellar, 25 (13.8%) were sellar, and 4 (2.2%) were presellar. The mean volume of the left sinus and the total sinus volume were significantly higher in men than in women (P<0.05). Carotid canal adhesion to the sphenoid sinus was observed in 20 patients (11.1%). No significant statistical difference was found between genders regarding the distribution of carotid canal adhesion, presence of accessory septa, or carotid canal protrusion. Similarly, the pneumatization of the anterior clinoid process, pterygoid process, and the greater and lesser wings of the sphenoid showed no gender-based significant differences. A significant statistical correlation was observed between left carotid protrusion and the pneumatization of the greater and lesser wings of the sphenoid, as well as pterygoid and anterior clinoid processes (P<0.05). On the right side, this correlation was not present with the pneumatization of the lesser wing. Regarding carotid canal adhesion, a significant correlation was only found with the pneumatization of the left pterygoid process (P<0.05).
Conclusion: The most common form of the sphenoid sinus was the postsellar type, and the mean total and left sinus volumes were greater in men. Gender was not found to be a reliable predictor for the extensive variations and high diversity of the sphenoid sinus anatomical characteristics.

 

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مجله دانشگاه علوم پزشکی گرگان Journal of Gorgan University of Medical Sciences
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