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Showing 1 results for Hejazian
Bahman Aghcheli , Seyed Amirreza Hejazian , Ghazaleh Alizad , Sadeghali Azimi , Alireza Tahamtan ,
Volume 27, Issue 4 (12-2025)
Abstract
Background and Objective: The coronavirus disease 2019 (COVID-19) pandemic has revealed significant variability in clinical outcomes driven by demographic, geographic, and underlying factors, highlighting the need for a better understanding of disease progression. This study was conducted to determine the clinical characteristics, outcomes, and predictors of disease severity among hospitalized COVID-19 patients in Gorgan, Iran.
Methods: This descriptive-analytical, cross-sectional study was conducted on the data of 736 hospitalized COVID-19 patients (58.6% male; mean age = 55 years; age range = 1–94 years) at the Fifth Azar Educational-Therapeutic Center in Gorgan during 2021. A convenience sampling method was employed, and patients were selected based on the completeness of their electronic medical records. Patients were categorized based on disease outcome (recovery/death) and disease severity (intensive care unit [ICU] admission/general ward admission). Demographic data, symptoms, and comorbidities were extracted from electronic health records. Inclusion criteria consisted of a confirmed diagnosis via reverse transcription quantitative polymerase chain reaction (RT-qPCR), while exclusion criterion included incomplete data or transfer to other medical centers.
Results: The mortality rate was 31.3%, occurring predominantly in the older adult age group (P<0.05). Due to disease severity, 21.2% of cases required ICU admission. Dyspnea was significantly associated with both mortality and disease severity (P<0.05). The prevalence of dyspnea was 62.6% among deceased patients compared to 37.4% in recovered patients. Comorbidities, such as cardiovascular diseases and chronic obstructive pulmonary disease (COPD), were significantly associated with increased mortality (P<0.05).
Conclusion: Old age and specific comorbidities were identified as key predictors of severe outcomes. Early identification of symptoms, particularly dyspnea, and targeted interventions are essential for high-risk groups.
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